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標題: 請幫忙在藥物研究! Folding@Home [打印本頁]

作者: berlo84    時間: 2005-1-1 16:19     標題: 請幫忙在藥物研究! Folding@Home

我們的目標: 瞭解蛋白質可摺疊、蛋白質族聚, 和相關疾病

什麼是蛋白質?它們是怎麼折疊的呢?
蛋白質是一個生物體系的網路基礎,它是一個個納米級電腦。在蛋白質實現它的生物功能之前,它們會把自己裝配起來,或者說是折疊;雖然蛋白質折疊對所以的生物來說是最基本的和最明確的事實,但它的折疊過程對人類而言仍然是個未解之謎。此外,當蛋白質沒有正確的折疊(誤折)無疑會產生嚴重的後果,包括許多知名的疾病,比方阿茲海默症(Alzheimer's),瘋牛病(Mad Cow, BSE),可傳播性海綿狀腦病(CJD),肌萎縮性脊髓側索硬化症(ALS),還有帕金森氏症(Parkinson's)。

电影壁纸桌面
Folding@home是一個研究蛋白質折疊,誤解,聚合及由此引起的相關疾病的分散式計算工程。我們使用聯網式的計算方式和大量的分散式計算能力來模擬蛋白質折疊的過程,並指引我們近期對由折疊引起的疾病的一系列研究。

您可以為我們做什麼?
您可以下載並運行我們的用戶端程式。我們的程式是這樣的,更多的電腦加入此工程,此工程計算的速度就越快。


更多細節


中文(請不要從中文網站下載版本5.03)------> http://www.equn.com/folding/
英語(Updated)-------> http://folding.stanford.edu/


請這裡直接下載


________________________________________________________________________


教學

中文 Thanks tkh7819 for translating into Chinese
HKEPC Folding@Home CLI 單處理器系統安裝教學
http://www.xsso.com.au/xtreme2k/fahsinglecht/

HKEPC Folding@Home CLI 雙處理器或P4 HT 系統安裝教學
http://www.xsso.com.au/xtreme2k/fahdualhtcht/

English Thanks xtreme2k
FAH Console Setup Guide for Single CPU systems
http://www.xsso.com.au/xtreme2k/fahsingle/

FAH Console Setup Guide for Dual CPU/P4 HT systems
http://www.xsso.com.au/xtreme2k/fahdualht/

________________________________________________________________________

Team for HKEPC is setup!!!
And team number is 41751!!!!
Yeah!!!
Hope this can make HKEPC even popular!!!!

[ 本帖最後由 berlo84 於 2008-11-12 11:32 編輯 ]
作者: berlo84    時間: 2005-1-1 16:20

This will be used to display the cert for HKEPC...










Make your AMD or INTEL computer even more useful!!!


NEWS UPDATE!!!

Folding@Home on the PS3: the Cure@PS3 project [size=-2]Quote from http://folding.stanford.edu/FAQ-PS3.html

INTRODUCTION

Since 2000, Folding@Home (FAH) has led to a major jump in the capabilities of molecular simulation. By joining together hundreds of thousands of PCs throughout the world, calculations which were previously considered impossible have now become routine. FAH has targeted the study of of protein folding and protein folding disease, and numerous scientific advances have come from the project.






Now in 2006, we are looking forward to another major advance in capabilities. This advance utilizes the new Cell processor in Sony’s PLAYSTATION 3 (PS3) to achieve performance previously only possible on supercomputers. With this new technology (as well as new advances with GPUs), we will likely be able to attain performance on the 100 gigaflop scale per computer. With about 10,000 such machines, we would be able to achieve performance on the petaflop scale. With software from Sony, the PlayStation 3 will now be able to contribute to the Folding@Home project, pushing Folding@Home a major step forward.

Our goal is to apply this new technology to push Folding@Home into a new level of capabilities, applying our simulations to further study of protein folding and related diseases, including Alzheimer’s Disease, Huntington's Disease, and certain forms of cancer. With these computational advances, coupled with new simulation methodologies to harness the new techniques, we will be able to address questions previously considered impossible to tackle computationally, and make even greater impacts on our knowledge of folding and folding related diseases.


ADVANCED FEATURES FOR THE PS3



The PS3 client will also support some advanced visualization features. While the Cell microprocessor does most of the calculation processing of the simulation, the graphic chip of the PLAYSTATION 3 system (the RSX) displays the actual folding process in real-time using new technologies such as HDR and ISO surface rendering. It is possible to navigate the 3D space of the molecule using the interactive controller of the PS3, allowing us to look at the protein from different angles in real-time. For a preview of a prototype of the GUI for the PS3 client, check out a screenshot or one of these videos ( 355K avi, 866K avi , 6MB avi , 6MB avi-- more videos and formats to come).

There is also a "bootleg" video of Sony's presentation on FAH that is now on YouTube (although the audio and video quality is pretty bad).



FOR MORE INFORMATION, PLEASE SEE

High Performance FAQ (http://folding.stanford.edu/FAQ-highperformance.html)
FAH FAQ (http://folding.stanford.edu/faq.html)
Folding community form (http://forum.folding-community.org)
PS3 FAQ (http://folding.stanford.edu/FAQ-PS3.html)



[ 本帖最後由 berlo84 於 2008-11-19 15:36 編輯 ]
作者: xtreme2k    時間: 2005-1-1 16:24


Hopefully more users will join

If you have already setup, please check these guide and MAKE SURE your settings are correct.

----
Some tips

- if you want the client to run at maximum speed, you need to use the CLI client
- if you have a HT capable cpu you run 2 client softwares at the same time for a 10-25% increase in performance.

[ Last edited by xtreme2k on 2005-1-2 at 09:13 PM ]
作者: loklokxp    時間: 2005-1-1 16:25

幫忙 i help
作者: althon65fx    時間: 2005-1-1 16:29

xtreme2k  在 2005-1-1 04:24 PM 發表:

Some tips

- if you want the client to run at maximum speed, you need to use the CLI client
- if you have a HT capable cpu you run 2 client softwares at the same time for a 10-25% increase in pe ...


What is CLi client?
作者: xtreme2k    時間: 2005-1-1 16:29

althon65fx  在 2005-1-1 07:29 PM 發表:

What is CLi client?


command line interface.

basically it means the text-based client.  No gfx no nothing.
作者: xtreme2k    時間: 2005-1-1 16:44

no support:confused:

:DISCUSS:
作者: berlo84    時間: 2005-1-1 16:56

i don't know how to use this...
作者: xtreme2k    時間: 2005-1-1 17:08

berlo84  在 2005-1-1 07:56 PM 發表:

i don't know how to use this...


Its actually not hard to use ga:DISCUSS:
作者: siacelestar    時間: 2005-1-1 17:13

using la...
作者: berlo84    時間: 2005-1-1 17:18

xtreme2k  在 1-1-2005 05:08 PM 發表:

Its actually not hard to use ga:DISCUSS:


i am using normal client....
作者: althon65fx    時間: 2005-1-1 17:20

berlo84  在 2005-1-1 05:18 PM 發表:

i am using normal client....


I'm using command line client...need less ram
作者: Keikei    時間: 2005-1-1 17:21

is it working properly?
作者: xtreme2k    時間: 2005-1-1 17:22

Keikei  在 2005-1-1 08:21 PM 發表:

is it working properly?


yes but your team number is 0.  You are not running for HKEPC:CRYBYE:
作者: Keikei    時間: 2005-1-1 17:24

xtreme2k  在 2005-1-1 05:22 PM 發表:

yes but your team number is 0.  You are not running for HKEPC:CRYBYE:


how can i run for epc?
作者: berlo84    時間: 2005-1-1 17:25

task bar icon--->right click--->config--->team number
enter our team number
作者: berlo84    時間: 2005-1-1 17:25

41751
作者: Keikei    時間: 2005-1-1 17:27

:welcome::welcome:
作者: Keikei    時間: 2005-1-1 17:28

其實work for epc同我之前有咩分別?
作者: berlo84    時間: 2005-1-1 17:32

they have team counting for this... the more we have the more popular are we! haha....
作者: Keikei    時間: 2005-1-1 17:42

berlo84  在 2005-1-1 05:32 PM 發表:

they have team counting for this... the more we have the more popular are we! haha....


i see
作者: fix118    時間: 2005-1-1 17:44

HELPING
呢種感覺好奇怪:D:D
好似好偉大咁
作者: berlo84    時間: 2005-1-1 17:46

fix118  在 1-1-2005 05:44 PM 發表:

HELPING
呢種感覺好奇怪:D:D
好似好偉大咁



me too! :CHEERS:

aleast this is really helping mankind...

frankly speaking... i used to do SETI@home.... but i found that doing this in protein and drug research are much more better so i started to do this!
作者: 掃馬想機    時間: 2005-1-1 17:47

整完好慢部腦
作者: berlo84    時間: 2005-1-1 17:48

掃馬想機  在 1-1-2005 05:47 PM 發表:

整完好慢部腦


u can set as screen saver.... when u computer is idle then it will run...
when u r using computer it will not run!

that solve ur problem....
作者: Bread    時間: 2005-1-1 17:49

一run就花畫面 :CRY:
作者: xtreme2k    時間: 2005-1-1 17:49

掃馬想機  在 2005-1-1 08:47 PM 發表:

整完好慢部腦


How much ram does your system have?
作者: HPI_PRO4    時間: 2005-1-1 17:50

Bread  在 2005-1-1 17:49 發表:

一run就花畫面 :CRY:


張wallpaper自己build :confused:
作者: 畢比特    時間: 2005-1-1 17:50

^^" joined...
作者: 掃馬想機    時間: 2005-1-1 17:52

xtreme2k  在 2005-1-1 05:49 PM 發表:

How much ram does your system have?


256

你支持下我買件512呢:DEV:
作者: berlo84    時間: 2005-1-1 17:52

Bread  在 1-1-2005 05:49 PM 發表:

一run就花畫面 :CRY:


if u r using windows XP u should use 5.03 not 4.00

here is the link

http://www.stanford.edu/group/pa ... Folding@Home503.EXE
作者: 掃馬想機    時間: 2005-1-1 17:53

如果得左又係美國人賺錢:CRYBYE:
作者: xtreme2k    時間: 2005-1-1 17:53

掃馬想機  在 2005-1-1 08:52 PM 發表:

256

你支持下我買件512呢:DEV:


I think thats the main problem.  Run it as a screensaver should be ok :DISCUSS:
作者: hihkufo    時間: 2005-1-1 17:55

部電腦full load緊 lu~:CRYBYE:
作者: Nutshell    時間: 2005-1-1 18:00

提示: 作者被禁止或刪除 內容自動屏蔽
作者: 畢比特    時間: 2005-1-1 18:00

打孖上+BT
作者: xtreme2k    時間: 2005-1-1 18:01

Nutshell  在 2005-1-1 09:00 PM 發表:

How about UD?
http://www.grid.org/home.htm


The way UD caculate the score for individual users/team is very poor.  Folding@home is much more fairer
作者: berlo84    時間: 2005-1-1 18:01

畢比特  在 1-1-2005 06:00 PM 發表:

打孖上+BT


both SETI and FOLDING will be very slow! :GIVEUP::GIVEUP::GIVEUP::GIVEUP:

:CRYBYE::CRYBYE::CRYBYE::CRYBYE::CRYBYE:

[ Last edited by berlo84 on 2005-1-1 at 06:03 PM ]
作者: xtreme2k    時間: 2005-1-1 18:02

畢比特  在 2005-1-1 09:00 PM 發表:

打孖上+BT


Check task manager see if each getting 50%.

A lot of the case it might not.
作者: Nutshell    時間: 2005-1-1 18:03

提示: 作者被禁止或刪除 內容自動屏蔽
作者: Bread    時間: 2005-1-1 18:03

HPI_PRO4  在 2005-1-1 05:50 PM 發表:

張wallpaper自己build :confused:


唔係呀 :CRY:
作者: althon65fx    時間: 2005-1-1 18:03

打3上@AXP-M 2600+@2.3Ghz 1.65W
作者: berlo84    時間: 2005-1-1 18:03

Bread  在 1-1-2005 06:03 PM 發表:

唔係呀 :CRY:


u use the wrong verision la!

5.03
作者: berlo84    時間: 2005-1-1 18:04

althon65fx  在 1-1-2005 06:03 PM 發表:

打3上@AXP-M 2600+@2.3Ghz 1.65W


ging!
作者: althon65fx    時間: 2005-1-1 18:09

berlo84  在 2005-1-1 06:04 PM 發表:

ging!


打8上:D:D
作者: xtreme2k    時間: 2005-1-1 18:11

althon65fx  在 2005-1-1 09:09 PM 發表:

打8上:D:D


No point running so many.

Its 1 per cpu is enough.  (except for P4HT).

If you run so many each unit will just run at 1/8 of the speed.  Some of the units have a expiry date.  If you submit them later than the expiry you will not get credited hence pointless.
作者: althon65fx    時間: 2005-1-1 18:12

xtreme2k  在 2005-1-1 06:11 PM 發表:

No point running so many.

Its 1 per cpu is enough.  (except for P4HT).

If you run so many each unit will just run at 1/8 of the speed.  Some of the units have a expiry date.  If you submit  ...


swhich them sin:D
作者: althon65fx    時間: 2005-1-1 18:14

Only me?:confused:
作者: xtreme2k    時間: 2005-1-1 18:15

althon65fx  在 2005-1-1 09:14 PM 發表:

Only me?:confused:


People's name will show up once they start returning the completed units
作者: fix118    時間: 2005-1-1 18:16

唔知做咩上網睇..
hkepc淨係睇到athlon_fx_55係度
我明明都入左嫁..
仲有run緊的..
但係就見唔到自己個名..
作者: berlo84    時間: 2005-1-1 18:16

althon65fx  在 1-1-2005 06:14 PM 發表:

Only me?:confused:


it takes time to update as many of us still in the old team....

result will be update when we download new data!

relax
作者: xtreme2k    時間: 2005-1-1 18:17

fix118  在 2005-1-1 09:16 PM 發表:

唔知做咩上網睇..
hkepc淨係睇到athlon_fx_55係度
我明明都入左嫁..
仲有run緊的..
但係就見唔到自己個名..


When you return a completed result, your username will then show.:DISCUSS:
作者: xtreme2k    時間: 2005-1-1 18:17

berlo84  在 2005-1-1 09:16 PM 發表:

it takes time to update as many of us still in the old team....

result will be update when we download new data!

relax


both of my machine running for epc now.  quitted the old WU.:DISCUSS:
作者: fix118    時間: 2005-1-1 18:18

xtreme2k  在 2005-1-1 06:17 PM 發表:

When you return a completed result, your username will then show.:DISCUSS:


oh..thx..
1%
2500+ 咋:CRY::CRY:
作者: shift2    時間: 2005-1-1 18:18

一開即hand機
mon 無野睇
作者: fix118    時間: 2005-1-1 18:18

shift2  在 2005-1-1 06:18 PM 發表:

一開即hand機
mon 無野睇


config??
作者: shift2    時間: 2005-1-1 18:19

fix118  在 2005-1-1 06:18 PM 發表:

config??


1.8a
i845
512
9550
作者: xtreme2k    時間: 2005-1-1 18:19

I highly recommend you guys the run the CLI(text mode) client.  It is faster than the graphical client significantly.
作者: xtreme2k    時間: 2005-1-1 18:20

shift2  在 2005-1-1 09:19 PM 發表:

1.8a
i845
512
9550


have you downloaded the correct 5.03 client?
作者: fix118    時間: 2005-1-1 18:20

xtreme2k  在 2005-1-1 06:19 PM 發表:

I highly recommend you guys the run the CLI(text mode) client.  It is faster than the graphical client significantly.


有圖果個食多d ram...
如果多d人參加就好啦:welcome::welcome::welcome:
作者: fix118    時間: 2005-1-1 18:22

簡體個網係冇5.0
英文果個先有
不如樓主將條link改成英文...
或者加條link link去英文果個下載頁
作者: shift2    時間: 2005-1-1 18:23

xtreme2k  在 2005-1-1 06:20 PM 發表:

have you downloaded the correct 5.03 client?


正是....你前X頁 貼果個
作者: xtreme2k    時間: 2005-1-1 18:24

shift2  在 2005-1-1 09:23 PM 發表:

正是....你前X頁 貼果個


From here?

http://folding.stanford.edu/download.html
作者: Keikei    時間: 2005-1-1 18:24

xtreme2k  在 2005-1-1 06:19 PM 發表:

I highly recommend you guys the run the CLI(text mode) client.  It is faster than the graphical client significantly.


點樣可以run text mode呀
作者: xtreme2k    時間: 2005-1-1 18:25

Keikei  在 2005-1-1 09:24 PM 發表:

點樣可以run text mode呀


http://folding.stanford.edu/download.html

download the 'text mode' 5.02 client.

just run the exe.

setup within and its done.
作者: shift2    時間: 2005-1-1 18:26

xtreme2k  在 2005-1-1 06:24 PM 發表:

From here?

http://folding.stanford.edu/download.html



但又好正常咁
可以按 開POWER >佢會關到機:drunk:
作者: Keikei    時間: 2005-1-1 18:27

xtreme2k  在 2005-1-1 06:25 PM 發表:

http://folding.stanford.edu/download.html

download the 'text mode' 5.02 client.

just run the exe.

setup within and its done.


咁我使唔使uninstall 5.03先install ga?
作者: xtreme2k    時間: 2005-1-1 18:27

shift2  在 2005-1-1 09:26 PM 發表:


但又好正常咁
可以按 開POWER >佢會關到機:drunk:


try the text mode client
作者: berlo84    時間: 2005-1-1 18:27

fix118  在 1-1-2005 06:22 PM 發表:

簡體個網係冇5.0
英文果個先有
不如樓主將條link改成英文...
或者加條link link去英文果個下載頁


thank you for ur info....

updated now!

thank you!
作者: xtreme2k    時間: 2005-1-1 18:27

Keikei  在 2005-1-1 09:27 PM 發表:

咁我使唔使uninstall 5.03先install ga?


yah uninstall it

5.02 text mode dont need to 'install'

just make a C:\fah
put the exe into it.

and run from there
作者: shift2    時間: 2005-1-1 18:29

xtreme2k  在 2005-1-1 06:27 PM 發表:

try the text mode client


LOAD左一陣都係ERROR :DISCUSS:
作者: xtreme2k    時間: 2005-1-1 18:31

shift2  在 2005-1-1 09:29 PM 發表:

LOAD左一陣都係ERROR :DISCUSS:


there must be something wrong with your system:Birthday:
作者: althon65fx    時間: 2005-1-1 18:59

:D:D

作者: berlo84    時間: 2005-1-1 19:00

:D:D
作者: xtreme2k    時間: 2005-1-1 19:02

lol~
作者: althon65fx    時間: 2005-1-1 19:15

2 working units la:D
作者: berlo84    時間: 2005-1-1 19:16

althon65fx  在 1-1-2005 07:15 PM 發表:

2 working units la:D


so fast??/

what CPU u using???
作者: xtreme2k    時間: 2005-1-1 19:17

althon65fx  在 2005-1-1 10:15 PM 發表:

2 working units la:D


but look at the points:Birthday::DISCUSS:
作者: fix118    時間: 2005-1-1 19:18

althon65fx  在 2005-1-1 06:59 PM 發表:

:D:D

梗係貼epc嫁啦

:D:D:D
作者: fix118    時間: 2005-1-1 19:19

xtreme2k  在 2005-1-1 07:17 PM 發表:

but look at the points:Birthday::DISCUSS:


張野會話0嫁:D:D:D:D:D
作者: fix118    時間: 2005-1-1 19:19

berlo84  在 2005-1-1 07:16 PM 發表:

so fast??/

what CPU u using???


係囉..
我e+先14/400
作者: althon65fx    時間: 2005-1-1 19:20

berlo84  在 2005-1-1 07:16 PM 發表:

so fast??/

what CPU u using???


AXP-M 2600+@ 2.4Ghz
作者: fix118    時間: 2005-1-1 19:22

althon65fx  在 2005-1-1 07:20 PM 發表:

AXP-M 2600+@ 2.4Ghz


好穩定啵...
我2500+2ghz都上唔到
作者: althon65fx    時間: 2005-1-1 19:23

fix118  在 2005-1-1 07:22 PM 發表:

好穩定啵...
我2500+2ghz都上唔到


B4 my 0423 2500+ can go to 2.4Ghz but not very stable,so sin sell it and buy this
作者: fix118    時間: 2005-1-1 19:24

althon65fx  在 2005-1-1 07:23 PM 發表:

B4 my 0423 2500+ can go to 2.4Ghz but not very stable


我0323:CHAIR:CHAIR:CHAIR:CHAIR
2500+上到3200+已經唔錯嫁啦:BABY::BABY:
作者: althon65fx    時間: 2005-1-1 19:24

fix118  在 2005-1-1 07:24 PM 發表:

我0323:CHAIR:CHAIR:CHAIR:CHAIR
2500+上到3200+已經唔錯嫁啦:BABY::BABY:


My 2500+@ 3200+ can run @ 1.575W
作者: fix118    時間: 2005-1-1 19:26

althon65fx  在 2005-1-1 07:24 PM 發表:

My 2500+@ 3200+ can run @ 1.575W


我試過1.8xV 上到3200+
不過入唔到windows
作者: xtreme2k    時間: 2005-1-1 19:31

how many users have we got running f@h?
作者: althon65fx    時間: 2005-1-1 19:31

xtreme2k  在 2005-1-1 07:31 PM 發表:

how many users have we got running f@h?


me
作者: hihkufo    時間: 2005-1-1 19:32

:GIVEUP:load左好耐架喇....好慢:CRY:
作者: fix118    時間: 2005-1-1 19:32

althon65fx  在 2005-1-1 07:31 PM 發表:

me


me2
16/400 ing..
作者: althon65fx    時間: 2005-1-1 19:32

hihkufo  在 2005-1-1 07:32 PM 發表:

:GIVEUP:load左好耐架喇....好慢:CRY:


23/400 lu:D
Command line better
作者: xtreme2k    時間: 2005-1-1 19:34

http://vspx27.stanford.edu/psummary.html

You guys can check how much 'points/credit' your work unit is worth once it is completed.
作者: hihkufo    時間: 2005-1-1 19:34

althon65fx  在 2005-1-1 07:32 PM 發表:

23/400 lu:D
Command line better

Command line 係邊度較?:D
我用緊1800+咋
作者: xtreme2k    時間: 2005-1-1 19:35

althon65fx  在 2005-1-1 10:32 PM 發表:

23/400 lu:D
Command line better


What CPU?  What work unit?
作者: althon65fx    時間: 2005-1-1 19:36

xtreme2k  在 2005-1-1 07:35 PM 發表:

What CPU?  What work unit?


AXP-M 2600+@2.4Ghz,work unit...where can see?
作者: xtreme2k    時間: 2005-1-1 19:36

althon65fx  在 2005-1-1 10:36 PM 發表:

AXP-M 2600+@2.4Ghz,work unit...where can see?


Check the command line console.  It say what 'protein' it is workign on
作者: xtreme2k    時間: 2005-1-1 19:37

We need more users running
作者: GuitaRKiDs    時間: 2005-1-1 19:38

xtreme2k  在 2005-1-1 07:31 PM 發表:

how many users have we got running f@h?


me
作者: fix118    時間: 2005-1-1 19:39

不過e+轉dos版果個...
會唔會重新計過??





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