請幫忙在藥物研究! Folding@Home

berlo84

我們的目標: 瞭解蛋白質可摺疊、蛋白質族聚, 和相關疾病

什麼是蛋白質？它們是怎麼折疊的呢？
蛋白質是一個生物體系的網路基礎，它是一個個納米級電腦。在蛋白質實現它的生物功能之前，它們會把自己裝配起來，或者說是折疊；雖然蛋白質折疊對所以的生物來說是最基本的和最明確的事實，但它的折疊過程對人類而言仍然是個未解之謎。此外，當蛋白質沒有正確的折疊（誤折）無疑會產生嚴重的後果，包括許多知名的疾病，比方阿茲海默症(Alzheimer's)，瘋牛病(Mad Cow, BSE)，可傳播性海綿狀腦病(CJD)，肌萎縮性脊髓側索硬化症(ALS)，還有帕金森氏症(Parkinson's)。

电影壁纸桌面
Folding@home是一個研究蛋白質折疊，誤解，聚合及由此引起的相關疾病的分散式計算工程。我們使用聯網式的計算方式和大量的分散式計算能力來模擬蛋白質折疊的過程，並指引我們近期對由折疊引起的疾病的一系列研究。

您可以為我們做什麼？
您可以下載並運行我們的用戶端程式。我們的程式是這樣的，更多的電腦加入此工程，此工程計算的速度就越快。


更多細節


中文(請不要從中文網站下載版本5.03)------> http://www.equn.com/folding/
英語(Updated)-------> http://folding.stanford.edu/


請這裡直接下載

________________________________________________________________________


教學

中文 Thanks tkh7819 for translating into Chinese
HKEPC Folding@Home CLI 單處理器系統安裝教學
http://www.xsso.com.au/xtreme2k/fahsinglecht/

HKEPC Folding@Home CLI 雙處理器或P4 HT 系統安裝教學
http://www.xsso.com.au/xtreme2k/fahdualhtcht/

English Thanks xtreme2k
FAH Console Setup Guide for Single CPU systems
http://www.xsso.com.au/xtreme2k/fahsingle/

FAH Console Setup Guide for Dual CPU/P4 HT systems
http://www.xsso.com.au/xtreme2k/fahdualht/

________________________________________________________________________

Team for HKEPC is setup!!!
And team number is 41751!!!!
Yeah!!!
Hope this can make HKEPC even popular!!!!

[ 本帖最後由 berlo84 於 2008-11-12 11:32 編輯 ]

berlo84

This will be used to display the cert for HKEPC...










Make your AMD or INTEL computer even more useful!!!


NEWS UPDATE!!!

Folding@Home on the PS3: the Cure@PS3 project [size=-2]Quote from http://folding.stanford.edu/FAQ-PS3.html

INTRODUCTION

Since 2000, Folding@Home (FAH) has led to a major jump in the capabilities of molecular simulation. By joining together hundreds of thousands of PCs throughout the world, calculations which were previously considered impossible have now become routine. FAH has targeted the study of of protein folding and protein folding disease, and numerous scientific advances have come from the project.






Now in 2006, we are looking forward to another major advance in capabilities. This advance utilizes the new Cell processor in Sony’s PLAYSTATION 3 (PS3) to achieve performance previously only possible on supercomputers. With this new technology (as well as new advances with GPUs), we will likely be able to attain performance on the 100 gigaflop scale per computer. With about 10,000 such machines, we would be able to achieve performance on the petaflop scale. With software from Sony, the PlayStation 3 will now be able to contribute to the Folding@Home project, pushing Folding@Home a major step forward.

Our goal is to apply this new technology to push Folding@Home into a new level of capabilities, applying our simulations to further study of protein folding and related diseases, including Alzheimer’s Disease, Huntington's Disease, and certain forms of cancer. With these computational advances, coupled with new simulation methodologies to harness the new techniques, we will be able to address questions previously considered impossible to tackle computationally, and make even greater impacts on our knowledge of folding and folding related diseases.


ADVANCED FEATURES FOR THE PS3



The PS3 client will also support some advanced visualization features. While the Cell microprocessor does most of the calculation processing of the simulation, the graphic chip of the PLAYSTATION 3 system (the RSX) displays the actual folding process in real-time using new technologies such as HDR and ISO surface rendering. It is possible to navigate the 3D space of the molecule using the interactive controller of the PS3, allowing us to look at the protein from different angles in real-time. For a preview of a prototype of the GUI for the PS3 client, check out a screenshot or one of these videos ( 355K avi, 866K avi , 6MB avi , 6MB avi-- more videos and formats to come).

There is also a "bootleg" video of Sony's presentation on FAH that is now on YouTube (although the audio and video quality is pretty bad).



FOR MORE INFORMATION, PLEASE SEE

High Performance FAQ (http://folding.stanford.edu/FAQ-highperformance.html)
FAH FAQ (http://folding.stanford.edu/faq.html)
Folding community form (http://forum.folding-community.org)
PS3 FAQ (http://folding.stanford.edu/FAQ-PS3.html)



[ 本帖最後由 berlo84 於 2008-11-19 15:36 編輯 ]

xtreme2k

Hopefully more users will join

If you have already setup, please check these guide and MAKE SURE your settings are correct.

----
Some tips

- if you want the client to run at maximum speed, you need to use the CLI client
- if you have a HT capable cpu you run 2 client softwares at the same time for a 10-25% increase in performance.

[ Last edited by xtreme2k on 2005-1-2 at 09:13 PM ]

loklokxp

幫忙 i help

althon65fx

xtreme2k  在 2005-1-1 04:24 PM 發表:

Some tips

- if you want the client to run at maximum speed, you need to use the CLI client
- if you have a HT capable cpu you run 2 client softwares at the same time for a 10-25% increase in pe ...

What is CLi client?

xtreme2k

althon65fx  在 2005-1-1 07:29 PM 發表:

What is CLi client?

command line interface.

basically it means the text-based client.  No gfx no nothing.

xtreme2k

no support:confused:

:DISCUSS:

berlo84

i don't know how to use this...

xtreme2k

berlo84  在 2005-1-1 07:56 PM 發表:

i don't know how to use this...

Its actually not hard to use ga:DISCUSS:

siacelestar

using la...